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The Twilio C# helper libraries are largely static, so you don't have to use DI, but sometimes you might want to. For example, you might want to create a custom TwilioRestClient that uses the HttpClientFactory features of .NET Core 2.1. In this post, I describe how to create a custom ITwilioRestClient, register it with the ASP.NET Core DI container, and inject it into a web API controller, so you can use it to send an SMS.